Can Bupivacaine Applied Intraoperatively into Paravertebral Muscle Tissues Reduce the Need for Postoperative Narcotic Analgesics and/or Nonsteroids?

Objective: Although the length of hospital stay after lumbar microdiscectomy operations, one most common surgical interventions in current neurosurgery practice, is quite short, nausea-vomiting and urinary retention, particularly postoperative pain, may prolong this period. Also, systemic side effects occur cases due to pharmacological agents applied for pain control. This study was conducted seek answers whether bupivacaine administered intraoperatively into paravertebral muscle mass decrease need narcotic analgesics and/or nonsteroidal anti-inflammatory drugs (NSAIDs). Materials Methods: Lumbar disc hernia patients with a similar history age, gender, body weight, level, preoperative score, analgesic use were included between 01.06.2020 31.06.2021 (n=48). The control group consisted who did not receive intramuscular during single-level operations under general anesthesia named as 1 (n=24). 2 After operation, assessment frequency morphine sulfate or pethidine hydrochloride performed Visual Analogue Scale (VAS). obtained data assessed one-way analysis variance, relationship parameters tested using Pearson correlation coefficient (r). Alpha significance value accepted <0.01. Results: It found comparisons groups that post-op VAS score (F=47.3; P=0.00), mobilization time (F=22.8; NSAIDs (F=12.7; (F= 12.6; P=0.00) statistically significant (P<0.01) bupivacaine. However, 2, although mean dose drug decreased from 11.46±16.45 mg 6.33±2.14 mg, it reported result (F=0.5; P=0.47) (P>0.01). determined there moderate positive mobilization. had strong above level (r=0.609) hospitalization (r=0.603). Conclusion: In which pre-op applied, operation significant, seen reduces NSAIDS-featured dexketoprofen trometamol significantly. These results make us think administration be effective controlling reducing additional analgesics.